Monday, March 22, 2010

UPDATE - AstraZeneca - Seroquel the anti-psychotic turned anti-depressant, how lies and misleading marketing work

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AstraZeneca - Seroquel the powerful tranquilizer anti-psychotic being advertised as an anti-depressant. How lies and misleading marketing work.

A hat tip goes out to pharmagossip for bringing this above ad to my attention. So now after misleading a jury in a New Jersey court room: this is how a so called responsible corporation "AZ" acts as they again purposely market and hide dangerous side effects associated with the drug Seroquel.

It's appears Big Pharma never learn when greed/profit are always their ultimate master; as here we go again with AZ using the same misleading lies and marketing tactics in Canada.

I have to wonder out loud when our Government, the DOJ, and the FDA will wake up and smell all this extreme marketing bullshit AZ constantly throws at consumers and doctors.

Bipolar depression doesn't consume you folks. AstraZeneca consumes you, they want to consume your bank account, and your personal health until death do you part.



Update/Addition: Some might be thinking to themselves that I'm being to harsh on these pharmaceutical corporate criminals here on this site even though Pharma Corporations have bought/purchased conflict of interest influence directly through many trumped up advocacy groups/organizations (direct Pharma marketing fronts such as with NAMI), being one of the largest lobbying spenders in federal and state capitals (including a wide open door to the Obama White House with untold millions in cash for policy deals), and how they have basically hooked/addicted university's and doctors on their steady flow of cash which in all cases tarnish and brings into the question the ethical and moral underpinnings in each of the proceeding entities mentioned here.

So your life and health have been virtually sold to the highest bidder so to speak.

My question is how many people have to be permanently disabled or killed before we start holding each link in this chain of blatant criminal inhumanity responsible for their unquenchable greed and evil self serving ways.

This is an interesting article over at Pharmalot worth reading related to the topic of Pharmaceutical corporate shenanigans within medicine and it's results upon public perception.
Psychiatrists And Pharma: Undue Influence?

You can also read about how anti-psychotics are being marketed to our armed forces with the devastating consequences that are created in their personal lives, diminish their effectiveness in war zone situations, and in the end may damage our national security. Why Are So Many Soldiers On Antipsychotics?

____________________________________________________

The comment section on this topic has been buzzing with such good information, that I have decided to add some of those comments to the front page here.

mike howard said...

One only has to look at Dr. Charles Schulz from the University of Minnesota and see how profitable pimping for AstraZeneca and seroquel is. It's never about researching for a cause/cure for mental illness, it's solely about just "treating" the symptoms and keeping the patient barely functioning as to keep the drug/cash flowing. Until America wakes up and realizes they have duped by the so-called psychiatric society things will just go on the same way. With psychiatric research its come down to "we don't care how the patient is doing, just how many have you enrolled. "First do no harm" went out the window long ago.


One only has to look at Dr. Charles Schulz at the University of Minnesota. He has the legend in his own mind mentality as far as pimping for AstraZeneca and falsifying Seroquel trial data. It's never about researching for a cause/cure for any psychiatric disease, it's more profitable to just keep people alive and "treat" the symptoms.

March 26, 2010 3:47 AM

Delete

Blogger Stephany said...

Well, here he is:

http://www.psychiatry.umn.edu/faculty/schulz/home.html

Founder and Director, Schizophrenia Program, MCV, 1980-83
Medical Director, Schizophrenia Module, University of Pittsburgh, 1983-86
Schizophrenia Research Branch, NIMH, 1986-89
Professor and Chair, Department of Psychiatry, Case Western Reserve University, 1989-99

Responsibilities/Activities in this Residency:
Head of Department of Psychiatry
Course director, Resident didactics
Lecturer, Resident didactics
Research supervisor

Research/Scholarly Interests:
Schizophrenia
Borderline personality disorder
Psychiatric illnesses in adolescents

--
http://www.ahrp.org/cms/content/view/548/70/

"By early 2000, Seroquel had been on the market for three years. Psychiatrist Charles Schulz MD--who received hundreds of thousands of dollars as a paid consultant to AstraZeneca and Eli Lilly--presented a report at the APA meeting that he said was based on his analysis of 1,800 patients in four separate trials. His conclusion: patients on Seroquel were more likely to show marked improvement...that Seroquel was significantly superior to other drugs.

However, the company's analysis of the data contradicted his pronouncements. Minnesota press reports describe internal emails by AstraZeneca officials, such as John Tumas, warning on March 23, 2000, after an internal company analysis of the raw data that:

"The data don't look good...What seems to be the case is that we were highlighting the only good stuff... It is clear that a claim of superiority for Seroquel over Haloperidol (Haldol) could not be generated using these data...In fact, I don't think we can even get a paper out of this."

Nevertheless, when Dr. Schulz presented his report, AstraZeneca issued a news release headlined "An analysis suggests Seroquel (R) has greater efficacy than Haloperidol." It quoted Schulz saying: "I hope that our findings help physicians better understand the dramatic benefits of newer medications like Seroquel.''

Glen Spielmans, an assistant professor of psychology at Metropolitan State University, who has reviewed the documents smelled something fishy: "These two things, they don't go together. Either the (company) analysis was wrong or Schulz's presentation was wrong."

Looks like another AZ pimp, like Reinstein and the rest of them, these people DESERVE PRISON TIME.

March 26, 2010 8:28 AM

Delete

Blogger Stephany said...

The above links to that doctor as well as this one could seriously be a post, but here it is:

http://www.twincities.com/ci_9292549

Patient dies in drug trial in the doctor's care

"He was then transferred to the University of Minnesota Medical Center, Fairview.

Weiss said discussions about research started right away at the hospital. Markingson was placed in Fairview's Station 12, a new unit at the time created to treat psychotic patients and screen them for research. Olson and Dr. Charles Schulz, head of the U's psychiatry department, helped launch the unit in part to enhance the hospital's startup schizophrenia program and meet the U's mandate to bring in more research dollars."

"A judge agreed Nov. 20 with Olson's new recommendation, requiring Markingson to follow the doctor's treatment plan. The next day, Markingson signed a consent form to be part of a national anti-psychotic drug study, Comparison of Atypicals for First Episode, or CAFE.

Weiss didn't understand. How could her son be deemed incapable of making decisions one day and then consent to a drug study the next?

The study, funded by drugmaker AstraZeneca and spread among 26 institutions, compared the effectiveness of three commonly used anti-psychotic drugs — Seroquel, Zyprexa and Risperdal."

"Full participation required Markingson to take one anti-psychotic drug for up to a year and to appear at the U for checkups. Markingson received AstraZeneca's Seroquel. As Subject 13, Markingson was worth $15,000 to the U, with some of that going to Olson's salary and the psychiatry department. Switching or adding medications could have disqualified Markingson and halted payments to Olson and the department from AstraZeneca."

"The state ombudsman raised concerns after Markingson's suicide, including the method of ensuring that patients were taking their pills and the ethics of one doctor both recruiting and treating a patient. The report also questioned whether Markingson was truly eligible for the study, because he wasn't diagnosed with schizophrenia until several weeks after he had enrolled."

---

We know how "informed consent" works in these places, what a tragic nightmare.

Update: April 14, 2010

This story never seems to end, just like AstraZeneca's criminal greed mongering never ends.

Here is a eye opening list of "Doctor Death's" gravy train payoffs from AZ to perpetrate dangerous lies as a spokes person and distribution icon for AstraZeneca Pharmaceuticals


Photo of Doctor Death

All 20 pages of them!

The back story of Doctor Death's and AstraZeneca's pay to poison scheme- @ pharmagossip Back story here.





15 comments:

Meg said...

I like the poll choices and I'm glad you're back. I was starting to go through Sassy Stan withdrawals, which is a side effect of my bloggeritus.

Stan said...

Nice of you to stop by Meg; though my posting maybe curtailed somewhat for a while, I will make a gallant Herculean effort to keep those corporate drug pimps coming back for more....he he he

Stephany said...
This comment has been removed by the author.
Borepatch said...

I'm with Meg.

;-)

Stephany said...

http://www.foxnews.com/story/0,2933,589778,00.html

You are better at this topic than I am, what the fuck?! (please write about it)

""In other words, if you're due a refund or some other federal benefit, and you didn't obtain qualified insurance, your refund or benefit will be tapped for your fee,” said Bill Ahearn, director of policy and communications for the Tax Foundation.

“People who aren't due any refunds or federal benefits will apparently face no collection action, as the IRS's hands will be effectively tied and it will be a truly voluntary tax."

mike howard said...

One only has to look at Dr. Charles Schulz at the University of Minnesota. He has the legend in his own mind mentality as far as pimping for AstraZeneca and falsifying Seroquel trial data. It's never about researching for a cause/cure for any psychiatric disease, it's more profitable to just keep people alive and "treat" the symptoms.

mike howard said...

One only has to look at Dr. Charles Schulz from the University of Minnesota and see how profitable pimping for AstraZeneca and seroquel is. It's never about researching for a cause/cure for mental illness, it's solely about just "treating" the symptoms and keeping the patient barely functioning as to keep the drug/cash flowing. Until America wakes up and realizes they have duped by the so-called psychiatric society things will just go on the same way. With psychiatric research its come down to "we don't care how the patient is doing, just how many have you enrolled. "First do no harm" went out the window long ago.

Stephany said...

Well, here he is:

http://www.psychiatry.umn.edu/faculty/schulz/home.html

Founder and Director, Schizophrenia Program, MCV, 1980-83
Medical Director, Schizophrenia Module, University of Pittsburgh, 1983-86
Schizophrenia Research Branch, NIMH, 1986-89
Professor and Chair, Department of Psychiatry, Case Western Reserve University, 1989-99

Responsibilities/Activities in this Residency:
Head of Department of Psychiatry
Course director, Resident didactics
Lecturer, Resident didactics
Research supervisor

Research/Scholarly Interests:
Schizophrenia
Borderline personality disorder
Psychiatric illnesses in adolescents

--
http://www.ahrp.org/cms/content/view/548/70/

"By early 2000, Seroquel had been on the market for three years. Psychiatrist Charles Schulz MD--who received hundreds of thousands of dollars as a paid consultant to AstraZeneca and Eli Lilly--presented a report at the APA meeting that he said was based on his analysis of 1,800 patients in four separate trials. His conclusion: patients on Seroquel were more likely to show marked improvement...that Seroquel was significantly superior to other drugs.

However, the company's analysis of the data contradicted his pronouncements. Minnesota press reports describe internal emails by AstraZeneca officials, such as John Tumas, warning on March 23, 2000, after an internal company analysis of the raw data that:

"The data don't look good...What seems to be the case is that we were highlighting the only good stuff... It is clear that a claim of superiority for Seroquel over Haloperidol (Haldol) could not be generated using these data...In fact, I don't think we can even get a paper out of this."

Nevertheless, when Dr. Schulz presented his report, AstraZeneca issued a news release headlined "An analysis suggests Seroquel (R) has greater efficacy than Haloperidol." It quoted Schulz saying: "I hope that our findings help physicians better understand the dramatic benefits of newer medications like Seroquel.''

Glen Spielmans, an assistant professor of psychology at Metropolitan State University, who has reviewed the documents smelled something fishy: "These two things, they don't go together. Either the (company) analysis was wrong or Schulz's presentation was wrong."

Looks like another AZ pimp, like Reinstein and the rest of them, these people DESERVE PRISON TIME.

Stephany said...

The above links to that doctor as well as this one could seriously be a post, but here it is:

http://www.twincities.com/ci_9292549

Patient dies in drug trial in the doctor's care

"He was then transferred to the University of Minnesota Medical Center, Fairview.

Weiss said discussions about research started right away at the hospital. Markingson was placed in Fairview's Station 12, a new unit at the time created to treat psychotic patients and screen them for research. Olson and Dr. Charles Schulz, head of the U's psychiatry department, helped launch the unit in part to enhance the hospital's startup schizophrenia program and meet the U's mandate to bring in more research dollars."

"A judge agreed Nov. 20 with Olson's new recommendation, requiring Markingson to follow the doctor's treatment plan. The next day, Markingson signed a consent form to be part of a national anti-psychotic drug study, Comparison of Atypicals for First Episode, or CAFE.

Weiss didn't understand. How could her son be deemed incapable of making decisions one day and then consent to a drug study the next?

The study, funded by drugmaker AstraZeneca and spread among 26 institutions, compared the effectiveness of three commonly used anti-psychotic drugs — Seroquel, Zyprexa and Risperdal."

"Full participation required Markingson to take one anti-psychotic drug for up to a year and to appear at the U for checkups. Markingson received AstraZeneca's Seroquel. As Subject 13, Markingson was worth $15,000 to the U, with some of that going to Olson's salary and the psychiatry department. Switching or adding medications could have disqualified Markingson and halted payments to Olson and the department from AstraZeneca."

"The state ombudsman raised concerns after Markingson's suicide, including the method of ensuring that patients were taking their pills and the ethics of one doctor both recruiting and treating a patient. The report also questioned whether Markingson was truly eligible for the study, because he wasn't diagnosed with schizophrenia until several weeks after he had enrolled."

---

We know how "informed consent" works in these places, what a tragic nightmare.

Stan said...

READER POLL RESULTS

We want to know the Reasons why you might take Seroquel

A. Hey, it was the only dope my corner drug dealer had in stock

B. I want to have diabetes, a sudden heart attack, and uncontrollable body movements

C. I want to do my part for Obama Care

D. I heard this was a great date drug

E. The ads were so convincing I figured why not put on 50 extra pounds

F. what a great way to not have to deal with life, Stupor is the new White Meat

G. I just want to get a head start on my new DSM-V made up diagnosis

H. Sure AZ is a greedy, criminal, and soulless corporation that doesn't give a flying Duck about us, but they need a little love too

I. all of the above, plus add in some little green aliens and the coming penguin insurgency

THE WINNER IS - all of the above

I thank you all for participating in this vitally important scientific research project.

Anonymous said...

Peace be with you Stan

You're one of my favorite people, and I never even looked into your eyes. You can e-mail me at the address in the upper right corner of my blog. Maybe you can help me with my decision.

love eternal
tad

PS: My "word verification" is "press."

Mark p.s.2 said...

Joking here?
Dr.Charles Schulz not-to-be confused with Charles Monroe Schulz (November 26, 1922 – February 12, 2000) cartoonist of Peanuts.
Unless it is a invented persona to filter Pharma money and sell scientific research.
Frank Adams, Frank Conners ,Frank Abagnale

Stephany said...
This comment has been removed by the author.
Meg said...

Stan, where are you?? I hoppe you are ok. I miss your comments!! They keep me on my toes!

Stan said...

Dear Meg:

Thanks for stopping by.

I've been very busy getting the real world stuff organized and placed in proper perspective.

Though I like blogging a lot, it is to be considered a extra luxury at the present time unfortunately.

I hope to be back here posting regularly in the near future.

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