1 Boring Old Man Blog has sounded the alarm bell; those that stand for ethical research, "DO NO HARM" instead of "Make More Money", those that stand against conflicts of interest, Bad Medicine, and Criminal Big Pharma Controlled Health Care Have heard the call & are now coming together with a multitude of ringing steeples in communities everywhere demanding not just substantive change, but accountability from those that have lied & deceived us from their scandalous medical ivory towers of profit & ego focused medicine.
1 Boring Old Man Blog
It has been ten years since study 329 was published. Martin Keller has stepped down as Chairman. Mina Dulcan is no longer editor of the Journal of the American Academy of Child and Adolescent Psychiatry. GSK has paid out a lot of money in fines and admitted that the study was negative or worse. Every SSRI bottle has a warning about suicidal thoughts in adolescents on SSRIs. Jon Jureidini, associate professor of psychiatry at the University of Adelaide, and Leemon McHenry, lecturer in philosophy at California State University, continue to push for a retraction [Of sophists and spin-doctors: industry-sponsored ghostwriting and the crisis of academic medicine, Conflicted medical journals and the failure of trust, Key opinion leaders and paediatric antidepressant overprescribing, Industry-sponsored ghostwriting in clinical trial reporting: a case study]. This story is well-summarized in the British Medical Journal by Melanie Newman [The rules of retraction].
There is no question that Study 329 and the reporting paper [Efficacy of Paroxetine in the Treatment of Adolescent Major Depression: A Randomized, Controlled Trial] is a paradigm for selective reporting, pharmaceutical industry’s interference in medical science, and a direct disavowal of the Hippocratic Oath. In addition, it reaches an indefensible conclusion – "Paroxetine is generally well tolerated and effective for major depression in adolescents." The question is, "Why hasn’t it been retracted?"
I encourage you to read the many fine post & writings on his blog; it will undoubtedly open your mind & burden your heart.
"Study 329 is still on the books, still saying, "Paroxetine is generally well tolerated and effective for major depression in adolescents." It’s a testimonial to the worst of times, and it needs to be retracted for the same reason that the statues and monuments of despots are destroyed when their regimes finally fall.." he wrote.