1 Boring Old Man Blog has sounded the alarm bell; those that stand for ethical research, "DO NO HARM" instead of "Make More Money", those that stand against conflicts of interest, Bad Medicine, and Criminal Big Pharma Controlled Health Care Have heard the call & are now coming together with a multitude of ringing steeples in communities everywhere demanding not just substantive change, but accountability from those that have lied & deceived us from their scandalous medical ivory towers of profit & ego focused medicine.
1 Boring Old Man Blog
It has been ten years since study 329 was published. Martin Keller has stepped down as Chairman. Mina Dulcan is no longer editor of the Journal of the American Academy of Child and Adolescent Psychiatry. GSK has paid out a lot of money in fines and admitted that the study was negative or worse. Every SSRI bottle has a warning about suicidal thoughts in adolescents on SSRIs. Jon Jureidini, associate professor of psychiatry at the University of Adelaide, and Leemon McHenry, lecturer in philosophy at California State University, continue to push for a retraction [Of sophists and spin-doctors: industry-sponsored ghostwriting and the crisis of academic medicine, Conflicted medical journals and the failure of trust, Key opinion leaders and paediatric antidepressant overprescribing, Industry-sponsored ghostwriting in clinical trial reporting: a case study]. This story is well-summarized in the British Medical Journal by Melanie Newman [The rules of retraction].
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There is no question that Study 329 and the reporting paper [Efficacy of Paroxetine in the Treatment of Adolescent Major Depression: A Randomized, Controlled Trial] is a paradigm for selective reporting, pharmaceutical industry’s interference in medical science, and a direct disavowal of the Hippocratic Oath. In addition, it reaches an indefensible conclusion – "Paroxetine is generally well tolerated and effective for major depression in adolescents." The question is, "Why hasn’t it been retracted?"
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I encourage you to read the many fine post & writings on his blog; it will undoubtedly open your mind & burden your heart.
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"Study 329 is still on the books, still saying, "Paroxetine is generally well tolerated and effective for major depression in adolescents." It’s a testimonial to the worst of times, and it needs to be retracted for the same reason that the statues and monuments of despots are destroyed when their regimes finally fall.." he wrote.
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Sad to say poor Stan didn’t get elected in the recent poll in Halifax, Canada. He failed by an impressively large margin.
Still, I’m sure he’ll be back at some point and perhaps by then we will have seen Study 329 retracted… it is still on the books, still saying, “Paroxetine is generally well tolerated and effective for major depression in adolescents.
It’s a testimonial to the worst of times, and it needs to be retracted for the same reason that the statues and monuments of despots are destroyed when their regimes finally fall”.
So says a retired physchiatrist, 1 Boring Old Man, in this article.
I have to agree that it’s high time Study 329 was retracted – and Marty Keller and Stan and the rest of the doctors that put their names to it were put under the spotlight and called to account for their actions.
I know it’ll never happen, but I can’t shake the feeling that Keller and Kutcher played their parts (together with GlaxoSmithkline) in what amounted to a physical assault on me. The study said Seroxat didn’t work, but rather than admit the fact, all parties lied and cheated in order to shore up the profile of what I can only describe as a harmful chemical that should never have been allowed to be prescribed so widely.
The bottom line for Keller, Kutcher et al was the money Glaxo paid them to lie about the efficacy and safety of Paxil/Seroxat.
The bottom line for Glaxo was (and still is) the billions in profit it makes each year.
Who picks up the pieces? – I do, every day – and so do all the other patients that were harmed by what Keller, Kutcher and Glaxo all knew to be a dangerous drug that didn’t actually work.
Read more in Alison’s Bass’ book Side Effects - the complete story of Study 329
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It is past time to say enough is enough....make your voice heard from the town square to the Representative halls of Washington DC...corruption & greed adversely effecting the health of America can NO LONGER BE TOLERATED...
A retraction of study 329 would be a nice beginning. Yet, what actually needs to happen to bring any form of effective change at this juncture; is a huge asterisk being placed by the name of each KOL involved on everything they have been associated with since 329 (which would include hundreds of studies & journal articles).
You can’t stop a runaway locomotive by simply throwing this single study on the tracks. The pharmaceutical machine will roll on by like someone placed a penny on the tracks for entertainment. These (criminals) doctors knew exactly what they were doing; it’s past time for substantial consequences to be distributed among them.
The analogy: You can’t kill the Greek mythological creature Typhon (Big Pharma) and Echidna (psychiatry) and their multitude of off spring by severing a single head. For we know that simply removing one head from these ravenous beast will not slow their rampage, or refrain them from inevitably devouring us all under the pretext of genotype and bio-markers…in essence society is being found guilty of mental disease until proven innocence or otherwise....all for profit
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